Hi xclusiv8
I use a X52 Pro, and the easiest is to keep the IL2 default key mappings or settings and then configure your own profiles (it takes a tad bit of time but worth it), I have numerous profiles for the different aircraft I fly... ie. fighters (singe and duel engines), bombers (dive and level bombing) and then one for jets. I just had to tinker around with my throttle settings a tad... if I remember I set up some trimming bands ( which were a b1tch to get working) etc on the hotas.
Sadly there is still no software to convert the old X45 and X52 profiles to the back then new X52 Pro.
Also check the Saitek website, there was a profile section and there was indeed a couple of flight sim profiles on there to download, check under the downloads section, scroll down to profiles, read the bumf and then download - here is a quick url to help you.
http://www.saitek.com/uk/down/profiles.htm
Hope this help you out.