I think multiple installations are the best thing to do by now,newest patch is an advance but ask yourself if you really want install it,for Ex. DS mod is developped for that,you do a fresh WoE install-patch and install,now is only an hardware problem!If you have a newest one DS mod will be greater,like WoI on it's debut.
YAP and YAP2 don't need that patch for example,and patch a whole modde install is a great risk!
Repeat do a multiple install-rename 'em old & new and you don't loose anything!
Maybe in next future another patch or improvements will solve something,but in my case...one year of modding is one year,I don't want erase these efforts is a few minutes!