A big thanks to you guys for trying to help.
Uncleal- I purchased this very joystick (Saitek ST290 Programmable Joystick with Throttle) a couple of years ago and changed the base to lefty but hated it as I had a problem when I used the X axis to bank the aircraft I would inadvertantly twisle the rudder/twist mechanism in the base which activated the aircrafts rudders. eventually, I got so infuriated with it that I gave it away to a mate for free as I couldn't hit a sausage due to yawing the aircraft at critical moments!! My CH Pro Rudder Pedals function fine with the joystick and continue to give me excellent realism with no conflicts whatsoever with or without the Saitek Throttle Quadrant installed.
Almccoyjr- One thing I have noticed is that I cannot configure any button from the throttle quadrant when in the OFF control config screen. It is as if the quadrant isn't being recognised at all in the sim. Therefore, I have saved a profile in Saiteks SST software and carried the binds into OFF, but unfortunately, no matter how many times I attempt to bind the left lever to use in OFF as the aircraft throttle and the middle lever in OFF for aircraft fuel mix, both don't work when in the cockpit in OFF. Only the Z-axis (right lever) works as the throttle and I have had to bind 2 switches underneath the lever to act as fuel rich/lean mix increments, which is okay as a temporary fix I suppose, but like I said previously, I purchased this throttle quadrant to use the levers not the switches for added realism and currently have 2 levers lying dormant which defeats the reason for purchasing the hardware in the first place. :(
Thanks again guys for your help so far. I will try to fathom out the problem if I can, otherwise I will continue using the present setup in OFF.