In order for VorpX to work, it has to be able to "hook" into the .exe of a game, and there are only a limited number of "hooks" supplied with the software. VorpX does not have a "hook" for CFS3.EXE, and none of the other available hooks can be repurposed for it, either. (Kitbashing and tweaking existing hooks is a common way to get "non-included" games working with VorpX). So... no 3D with VorpX.
However, VR rigs make superb (if pricey) head-tracking solutions. Basically, you play the game as normal inside your VR headset, using whatever virtual desktop/bigscreen software you choose. The free OpenTrack, run at the same time, provides the head-tracking.
Currently, I'm using a Quest 2, so I:
* establish the PC link with the Q2
* launch Virtual Desktop PC (like $15 on Steam, provides awesome, adjustable desktop viewing)
* This brings up my desktop inside my Q2
* Launch OpenTrack (it's configured to use my Q2 as an input) - this effectively takes care of WOFF2's TrackIR hook
* Launch WOFF2
I now have a nice big screen inside my headset with headtracking. The downside, of course, is that you can't see your keyboard. Which you actually totally can, if you peer down your nose and squint. So, just like any sim, you need a HOTAS, and you DEFINITELY need a HOTAS if you're strapping stuff to your face.
TL;DR: No, VorpX does not work with WOFF2. There's other ways to do hacked-together stereoscopic 3D with virtual desktop and reshade 3D, but I've done it, it's fiddly, and not worth the hassle.